(Tert-Butoxy)Carbonyl Nle-OH (Syrup)
N-Boc-L-norleucine
CAS: 6404-28-0
Molecular Formula: C11H21NO4
(Tert-Butoxy)Carbonyl Nle-OH (Syrup) - Names and Identifiers
| Name | N-Boc-L-norleucine |
| Synonyms | Boc-Nle-OH BOC-L-NORLEUCINE Boc-L-norleucine N-Boc-L-norleucine Boc-(S)-2-aminohexanoicacid N-(tert-butoxycarbonyl)norleucine N-(tert-butoxycarbonyl)-L-norleucine (Tert-Butoxy)Carbonyl Nle-OH (Syrup) Norleucine, N-carboxy-, N-tert-butyl ester (2S)-2-[(tert-butoxycarbonyl)amino]hexanoate N-[(1,1-Dimethylethoxy)carbonyl]-L-norleucine (S)-2-((tert-Butoxycarbonyl)aMino)hexanoic acid |
| CAS | 6404-28-0 |
| InChI | InChI=1/C11H21NO4/c1-5-6-7-8(9(13)14)12-10(15)16-11(2,3)4/h8H,5-7H2,1-4H3,(H,12,15)(H,13,14)/p-1/t8-/m0/s1 |
(Tert-Butoxy)Carbonyl Nle-OH (Syrup) - Physico-chemical Properties
| Molecular Formula | C11H21NO4 |
| Molar Mass | 231.29 |
| Density | 1.1202 (rough estimate) |
| Boling Point | 373.37°C (rough estimate) |
| Flash Point | 172.8°C |
| Vapor Presure | 3.14E-06mmHg at 25°C |
| BRN | 3608376 |
| pKa | 4.02±0.21(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.4425 |
| MDL | MFCD00037270 |
(Tert-Butoxy)Carbonyl Nle-OH (Syrup) - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29224985 |
(Tert-Butoxy)Carbonyl Nle-OH (Syrup) - Introduction
N-Boc-L-norleucine(N-Boc-L-norleucine) is an amino acid derivative. Its structure contains a norleucine residue and a protecting group (Boc-protecting group) attached to the amino group. Its chemical formula is C11H21NO4.
N-Boc-L-norleucine is a white crystalline solid, soluble in organic solvents such as methanol, ethanol and dimethyl sulfoxide, but insoluble in water. Its melting point is about 74-78 degrees Celsius.
N-Boc-L-norleucine are mainly used in peptide synthesis and drug research in organic synthesis. As an amino acid derivative, it can be used as an amino acid component in drug molecules or for the synthesis of biologically active polypeptides or proteins.
The preparation method of the N-Boc-L-norleucine is generally realized by chemical synthesis. The most common method is to react norleucine with a Boc-protecting group to form N-Boc-L-norleucine. This reaction is generally carried out by the thionamide reduction method or the nitrosotrimethylmethane method.
With regard to safety information, the N-Boc-L-norleucine does not have obvious hazards to the human body under normal conditions. However, it is a chemical that needs to be handled following general laboratory safety practices. Contact with skin and eyes should be avoided and used in a well-ventilated place. During the operation, appropriate personal protective equipment such as gloves, goggles and laboratory coats should be worn.
N-Boc-L-norleucine is a white crystalline solid, soluble in organic solvents such as methanol, ethanol and dimethyl sulfoxide, but insoluble in water. Its melting point is about 74-78 degrees Celsius.
N-Boc-L-norleucine are mainly used in peptide synthesis and drug research in organic synthesis. As an amino acid derivative, it can be used as an amino acid component in drug molecules or for the synthesis of biologically active polypeptides or proteins.
The preparation method of the N-Boc-L-norleucine is generally realized by chemical synthesis. The most common method is to react norleucine with a Boc-protecting group to form N-Boc-L-norleucine. This reaction is generally carried out by the thionamide reduction method or the nitrosotrimethylmethane method.
With regard to safety information, the N-Boc-L-norleucine does not have obvious hazards to the human body under normal conditions. However, it is a chemical that needs to be handled following general laboratory safety practices. Contact with skin and eyes should be avoided and used in a well-ventilated place. During the operation, appropriate personal protective equipment such as gloves, goggles and laboratory coats should be worn.
Last Update：2024-04-09 20:45:29
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